Association of rs11209032 and rs1004819 Polymorphisms in Interleukin-23 Receptor Gene With Ankylosing Spondylitis
نویسندگان
چکیده
منابع مشابه
Association of Interleukin-10 gene polymorphisms with ankylosing spondylitis.
OBJECTIVE Genetic polymorphisms of the Interleukin-10 (IL-10) promoter have been implicated in several autoimmune diseases, including seronegative spondyloarthropathies. This study investigated whether single nucleotide polymorphisms (SNPs) and haplotypes of IL-10 are associated with ankylosing spondylitis (AS), a common subtype of spondyloarthritis (SpA). METHODS The serum levels of IL-10 we...
متن کاملASSOCIATION OF HLA-B27 WITH ANKYLOSING SPONDYLITIS IN ISFAHAN, IRAN
Using a standard microcytotoxicity (NIH) technique of tissue typing, the HLA-B27 antigen was identified in 30 out of 34 patients (HH.2%) with classical ankylosing spondylitis (AS), compared to 6 out of 70 controls (H.6%) (P < 0.005). We also found this antigen in 8 out of 76 (10.5%) patients with non-AS arthritis.
متن کاملInterleukin-1beta and interleukin-1 receptor antagonist gene polymorphisms in ankylosing spondylitis.
OBJECTIVE Since ulcerative colitis and Crohn's disease, which are associated with ankylosing spondylitis (AS), have been found to be variably associated with the IL-1B and the IL-1RN genes encoding interleukin-1beta (IL-1beta) and the interleukin-1 receptor antagonist (IL-1ra), we have investigated whether these polymorphisms in IL-1B and IL-1RN are also involved in AS. METHODS DNA was isolat...
متن کاملAssociation between rs7517847 and rs2201841 polymorphisms in IL-23 receptor gene and risk of ankylosing spondylitis: a meta-analysis
To comprehensively evaluate the association between rs7517847 and rs2201841 polymorphisms in the Interleukin-23 (IL-23) receptor gene and ankylosing spondylitis (AS), a meta-analysis was performed. The Pubmed, Embase, MEDLINE, Cochrane, China National Knowledge Infrastructure (CNKI), VIP, Wanfang and China Biology Medicine disc (CBMdisc) databases were searched to identify eligible studies on r...
متن کاملassociation between interleukin-23 receptor r381q gene polymorphism and asthma
the snp (rs11209026, arg381gln, r381q) in the il-23 receptor (il23r) confers protection against multiple inflammatory diseases, representing one of the most significant human genetic polymorphisms in inflammatory diseases. we, therefore, investigated the association between il-23 r r381q gene polymorphism and asthma.this case-control study was performed on 209 patients, and 200 healthy controls...
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ژورنال
عنوان ژورنال: Archives of Rheumatology
سال: 2016
ISSN: 2148-5046
DOI: 10.5606/archrheumatol.2016.5827